Organizer: Génome Québec (GQ), in partnership with Cystic Fibrosis Canada
Génome Québec and Cystic Fibrosis Canada are pleased to announce the launch of their competition “Tackle rare, orphan CFTR mutations”. This $1.2 million competition aims to support research on rare mutations of CFTR for which no treatment is available with the long-term goal of developing novel therapies through the following objectives:
- Specifically address forms of cystic fibrosis caused by rare mutations which are not responsive to currently available treatments and thereby take forward the Cystic Fibrosis community priorities. Targeted mutations are class I mutations (nonsense, frameshift, splicing) that don’t produce functional CFTR protein.
- Improve the understanding of the mechanism of these mutations and/or lay the basis for the development of novel therapies, using omics approaches.
For more details on the competition requirements, please see the request for applications document below.
Funding Overview
Research teams will develop a research program with concrete activities and deliverables that support the above-mentioned objectives.
This program will finance projects with a total budget from $300,000 up to $600,000 each (no co-funding required).
This competition is open only to researchers affiliated with an eligible institution in Québec.
Applications must be submitted through Génome Québec. The process will consist of a mandatory registration and an application (see below for the documents).
The important dates and key steps of the application process for this competition are as follows:
| Date | Stage |
| June 12, 2024 | Competition launch |
| August 27, 2024, noon (EDT). | Mandatory registration deadline: Please submit the registration form to R-CFTR@genomequebec.wp.vortexdev.com |
| Early September 2024 | Notice of eligibility |
| October 16, 2024, noon (EDT). | Application submission deadline: Please submit your application (including the budget and statement(s) of work for external services) to R-CFTR@genomequebec.wp.vortexdev.com |
| Mid-December 2024 | Meeting of the evaluation committee |
| January 2025 | Notice of award |
| April 1, 2025 | Start of the project |
- Génome Québec Financial Guidelines
- EDI – guiding principles
- Request for Applications
- Registration Form
Full Application Form (provided at notice of eligibility) – only teams having submitted an eligible registration will be invited to apply.
To obtain more details related to the initiative, please contact Annina Spilker, Manager of programs and strategic initiatives, by email at R-CFTR@genomequebec.wp.vortexdev.com.