FFPE sample archives contain a wealth of valuable information for human cancer studies. The nucleic acids contained in these samples are generally fairly degraded, low in abundance and chemically modified. As a result, they may perform less well in most whole-genome genotyping and expression studies. We have tested new products and are proud to now be able to offer these genotyping and methylation analysis technologies for FFPE samples.
Illumina BeadChips
Using a simplified procedure, all Illumina’s commercial microarrays, custom or semi-custom, can be used for FFPE samples. This procedure uses the “Infinium FFPE DNA Restoration Solution”, which simplifies the initial selection of samples of sufficient quality to repair damaged DNA in the samples for the subsequent genotyping or methylation analysis.