Project leader: Carl Julien
Sector: Agrifood
Budget: 299 999,00 $

Start date: 01 July 2025 End date: 30 June 2027

User: Probiotech International

Parasitic infections caused by worms result in billions of dollars in losses worldwide in the agricultural sector, particularly in livestock production.

Since the 1970s, dewormers have been the treatment of choice, but increasing drug resistance, as observed by producers and breeders, is compromising its effectiveness. Alternatives to dewormers are needed to limit the use of drugs in livestock. In this study, we will evaluate whether plant extracts can serve as a substitute to dewormers. Molecular mechanisms will be studied using a functional genetic approach with the C. elegans worm and omics research techniques.

The results of this research could have significant economic, environmental and social benefits in Québec. The plant extracts could help boost the competitiveness of producers and breeders, prevent the development of drug resistance and improve animal welfare. Better efficiency and less waste would also have a positive environmental impact by reducing inputs and, in turn, greenhouse gas emissions. Cutting back on the use of synthetic molecules in livestock meets consumer demand, while supporting biodiversity preservation, reducing drug resistance and lowering the chemical contamination of waterbodies.

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